weight loss ketones pregnancy | HOW CHROMOSOMES CAUSE MISCARRIAGE

weight loss ketones pregnancy

Explanation of How Chromosomal Abnormalities Result In Miscarriage

Miscarriage and Recurrent Miscarriage

Wow... the more I read articles like this one, the more I realize how much of getting pregnant and staying pregnant involves luck.
My site:  www.getpregnantover40.com
 The study mentioned below looked at egg formation and the arrangement of chromosomes. It isnt a perfect process and getting the right number of chromosomes almost seems like a "hit and miss" process. Read more:

During meiosis, fibres called microtubules attach themselves to the centre (kinetochore) of the chromosomes. The microtubules act like fishing lines and once a chromosome is caught it is pulled to the opposite side of the cell from its partner.

But, before the microtubules hook the chromosomes, the researchers noticed that they herd them together into the centre of the cell. Despite this repositioning, almost 90 per cent of chromosomes were let off the hook only to be re-caught.

See Also: Miscarriage Over 40 (www.getpregnantover40.com)

"We saw that they [the microtubules] have to go through several tries before getting the connection right," says Ellenberg.
Third time lucky

In fact, some chromosomes were released up to six times, though most averaged three. Ellenberg says this means that the pathway that corrects the errors by uncoupling the chromosome and the microtubule is therefore heavily used and thus more prone to making mistakes — resulting in too few or too many chromosomes in the egg.

"Our findings provide a plausible explanation for the high rate of errors during egg formation."

Ellenberg adds that their observations make error correction proteins good candidates for age-related infertility.

"They form the basis to focus our future work on age-related female infertility, as it seems very likely that a component of the pathway that corrects these errors will be involved. The individual proteins that make up the machinery to correct the errors may simply not have a sufficiently long life-span to function well in very old oocytes," he says.

From:  www.cbc.ca

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kim pregnancy weight loss | UNEXPLAINED INFERTILITY WE DONT KNOW

kim pregnancy weight loss

The expression "unexplained infertilty" means that the medical community has no idea why youre not getting pregnant.
 If youre trying to conceive over 40, your age is a neat a tidy "explanation" for your failure to conceive or an explanation of recurrent miscarriage.

Unexplained Infertility Means The Doctors Have No Idea Why Youre Not Getting Pregnant

How did I deal with this? Well in an odd sort of way, part of my motivation to get pregnant naturally came from these "naysaying" doctors. I was going to prove them wrong.

How Dare You Tell Me Im Too Old To Have A Baby!

 I would frequently think to myself, "How dare you tell me Im too old to have a baby --- you just wait - you dont know who youre dealing with". Nobody actually came right out and said I was too old, but the message was there.

Its funny, but when I did finally succeed, one of the doctors who was quite negative about my chances of getting pregnant was bouncing off the walls with excitement. I think they really do want you to succeed and as more of us do, perhaps their attitudes toward older women will change.  You have to realize that Reproductive Endocrinologists (or fertility doctors) see the worst cases, they approach each couple with pessimism.

Unexplained Infertility May Not Exist

Here is an article about how the diagnosis of unexplained infertility may actually not exist...it mentions that perhaps it should be changed to "undiagnosed infertility". Read more:

SEE ALSO: GET PREGNANT NATURALLY (getpregnantover40.com)

Conclusions

We have presented evidence that the non-diagnosis of UI is, at best, highly subjective and inaccurate and, at worst, non-existent. Indeed, were it to be preserved, one would, at a minimum, have to accept the notion that a diagnosis of UI always has to be seen as provisional and subject to revisions. Any serious attempt to improve the didactic terminology in the field of reproductive medicine, would, however, suggest that there is no longer a place for such a diagnostic entity. A better effort should be undertaken to develop reliable tools to diagnose, hitherto often undiagnosed, conditions of endometriosis, tubal disease, premature ovarian ageing and immunological infertility, which are often misdiagnosed for UI. Diagnostic terminology should be based on evidentiary diagnostic findings and not on their absence.

Even the best, and most accurate, diagnostic approach will leave some patients without a specific diagnosis. We would argue that such patients should be considered ‘undiagnosed‘, rather than have a formal diagnosis of UI attached to them. After all, they do not have a diagnosis! 

from: 
oxfordjournals.org

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weight loss journey during pregnancy | LUTEAL PHASE DEFECT AND VITAMIN C

weight loss journey during pregnancy

Luteal Phase Defect and Vitamin C

I have always associated vitamin C with the immune system.
 This article, however talks about how vitamin C may also play a role in regulating hormones which may hep with conditions like luteal phase defect.  Luteal phase defect is when your hormones fall too fast in the second half of your cycle.

SEE ALSO: FOODS FOR FERTILITY (getpregnantover40.com)

From the article:

A number of factors can cause luteal phase defect. Recent findings have suggested that oxidative damage may play a role, and antioxidant levels, such as vitamin C, vitamin E, and glutathione, were found to be significantly lower in women with luteal phase defect and recurrent miscarriages than in healthy women. The potential benefits of antioxidant vitamin supplementation have not been previously explored.

One hundred fifty women with luteal phase defect seeking medical attention for infertility were enrolled in the current study. Levels of estrogen and progesterone were monitored for three menstrual cycles. The participants were randomly assigned to receive 750 mg of vitamin C per day or no treatment beginning at the onset of the third cycle of the study. During the third cycle, progesterone levels increased significantly in women receiving vitamin C but did not change in women receiving no treatment. Estrogen levels also increased in the treatment group but not the untreated group. Moreover, there was a significantly higher pregnancy rate in the vitamin C group than in the untreated group: 25% of the women receiving vitamin C became pregnant within six months of starting treatment, while only 11% of untreated women became pregnant in the same time period.

basyrcenter.org

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